UAMS Myeloma Researchers on Team Analyzing Disease's Genetic Fingerprints -- Cancer Cell Publishes Work That Could Lead to New Treatments
Little Rock, AR (ContentDesk) April 11, 2006 -- Researchers at the University of Arkansas for Medical Sciences (UAMS -- http://www.uams.edu) are part of a team that has identified that multiple myeloma (http://myeloma.uams.edu), a cancer of the blood, could actually be several different diseases at the cellular level with a potential for genetically targeted treatments that could extend to other forms of cancer.The research is published in the April 2006 issue of journal Cancer Cell. The article, "Tracking genome changes during cancer initiation, progression and treatment sheds light on multiple myeloma," is now available online at http://www.cancercell.org/.UAMS myeloma researcher John D. Shaughnessy Jr., Ph.D., was one of three lead authors of the study, along with Ron A. DePinho, M.D., of the Dana-Farber Cancer Institute/Harvard Medical School, and Cameron Brennan, M.D., of Memorial Sloane-Kettering Cancer Center. Shaughnessy is director of the Lambert Laboratory of Myeloma Genetics in the Myeloma Institute for Research and Therapy (http://myeloma.uams.edu), which is part of the Arkansas Cancer Research Center at UAMS (http://www.acrc.uams.edu), and an associate professor in the UAMS College of Medicine (http://www.uams.edu/com)."The new research, based on analysis of myeloma cells, is a significant step in understanding the genetic basis of myeloma development and progression," Shaughnessy said.
"The study suggests that myeloma consists of at least seven different genetic subtypes of disease," he said."This represents a watershed in myeloma research since multiple myeloma's genetic complexity had previously kept us from determining if it was actually more than one disease," Shaughnessy said. "Now we can begin to better separate patients by the effect myeloma is having on them at the genetic level and develop targeted treatments based on that knowledge."Development of so-called targeted therapies, aimed at specific genetic mutations and biochemical pathways affected within cancer cells is being utilized now in some cancers like chronic myelogenous leukemia and is a hope for all cancers."Several of the genes identified in the study also are associated with unrelated cancers, including pancreatic, lung, breast and ovarian cancer.About the Myeloma Institute for Research and Therapy:The MIRT (http://myeloma.uams.edu) continues to be at the forefront of myeloma research with this latest publication. Studies of myeloma treatment methods, led by Bart Barlogie, M.D., Ph.D., director of the MIRT, were published in the April issue of Blood, the journal of the American Society of Hematology as well as the March 9 issue of the New England Journal of Medicine.Barlogie's work was recognized in March when the organization responsible for publishing the annual America's Top Doctors named him a national physician of the year. The selection was based on nominations submitted by physicians profiled in America's Top Doctors.Multiple myeloma (http://myeloma.uams.edu) is a type of cancer that involves plasma cells -- white blood cells that produce antibodies. It is the second most common cancer of the blood.When plasma cells become cancerous, they reproduce uncontrollably and crowd out healthy red and white blood cells, preventing them from fighting infection and carrying oxygen throughout the body.
Bone destruction is a common manifestation of myeloma. The malignant cells also produce a type of protein that can cause kidney failure.Research at the MIRT has more than doubled the annual survival rate of a myeloma patient upon diagnosis from three years to seven years and beyond.About the University of Arkansas for Medical Sciences (UAMS):
UAMS is the state's only comprehensive academic health center, with five colleges, a graduate school, a medical center, five centers of excellence and a statewide network of regional centers. UAMS has about 2,320 students and 690 medical residents. It is one of the state's largest public employers with almost 9,000 employees, including nearly 1,000 physicians who provide medical care to patients at UAMS, Arkansas Children's Hospital and the VA Medical Center. UAMS and its affiliates have an economic impact in Arkansas of $4.3 billion a year.Contact:Andrea Peel, 501-686-8996Wireless Phone, 501-351-7903http://www.uams.edu | http://myeloma.uams.edu.
Wired. It's More than the Name of a Magazine
Recently I posted a couple of articles on my blog that discussed the new products that were being introduced at February's International Homebuilder's Tradeshow in Orlando, and how they will ultimately change the way new homes are built in the future. (See: http://www.stlagent.com for these articles).Some of the products are novelty items (like a magnetic chalkboard door), some are trendy (like a built-in coffee machine), but some will truly change the landscape of new home construction for years to come by addressing issues like environmental changes (such as the plethora of recycled products designed to reduce builder's consumption of wood).But to really understand many of these new products and why their development is important, you have to look at the underlying changes in our society and culture that drives their inventions. Steel, for example, was invented to build skyscrapers which could house the hordes of people cramming into...
Wired. It's More than the Name of a Magazine
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Plasma TV A Big Screen For a Little Room
One of the biggest drawbacks of the big screen television is the space needed for the television set itself. The plasma TV technology has made it possible to incorporate a big screen television into a small room. To understand how this change came about, briefly consider the difference in technology between a traditional television set and a plasma TV.For the majority of time that television sets have been used as part of the home entertainment system, the television picked up a analog signal sent out by a broadcaster. That signal was analyzed by the television set and cathode ray tubes lit up the screen of the television. Thousands of tiny pixels make up the screen of the TV set in three colors - red, blue and green.
Combinations of colors gave different hues as seen in real life and the result was a movie that (as nearly as possible) duplicated what we see in the real world. Digital television systems have increased the quality of the picture though many signals are still in...
Plasma TV A Big Screen For a Little Room
Plasma tv > Plasma TV A Big Screen For a Little Room
Magnesium Oxide
Magnesium oxide has the chemical formula MgO. It is a white or colorless, odorless compound. It is extracted from seawater or underground brine. It is also formed by the calcination of magnesium minerals such as magnesium carbonate and magnesium hydroxide. Magnesium oxide is present in the mineral periclase.
Periclase is multihued, which makes it a substitute for gemstones. Periclase is also the substance responsible for providing streaks to white marble.
Medicinally, magnesium oxide is used as a short-term laxative for rapid elimination of the bowels, especially before surgery. It is also used as a dietary supplement when the amount of magnesium in the diet is not sufficient. Magnesium oxide use is not recommended for persons with heart and kidney problems. It is also not advisable for pregnant and lactating women.
Magnesium oxide can interfere with other drugs like warfarin, aspirin, ranitidine, etc.
Apart from medicine, magnesium oxide also...
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Scala?s Executive Vice President to Participate on Digital Signage Summit Panel Discussion
Scala Inc. (www.scala.com), the world's leading software platform for digital signage, today announced Jeff Porter, Executive Vice President of Scala Inc., will join Brad Gleeson, President and COO of ActiveLight and Al Jensen, Senior Director of Marketing for Barco in a panel discussion, sponsored by The Strategy Institute. Mr. Porter, et al, widely recognized as industry experts, will be speaking on the State of the Digital Signage Industry: Leading Suppliers Share Insight and Answer Your Questions at the Digital Signage Summit in New York City, scheduled for Tuesday, April 26 at 10:45 AM EDT at Bridgewaters in New York City.The panel discussion will highlight the issues of an emerging industry and share insider views about the most recent developments and global trends affecting the industry; a must see discussion for companies interested in digital signage networks."With the plummeting cost of Plasma and LCD screen technology and...
Scala?s Executive Vice President to Participate on Digital Signage Summit Panel Discussion
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OnePAL Adds Searchable Coupons, Holiday Gift Idea Center
Minneapolis (ContentDesk) December 7, 2005 -- Online comparison shopping company OnePal LLC announces the addition of coupons from over 1,000 leading merchants for products such as electronics, computers, software, books, games and music to its website. Customers can search OnePAL.coms coupons by keyword, merchant or product and simply click on the resulting link to be redirected to the website of the participating merchant, where they can enter the coupon code to realize instant savings.Jamison Geisler, Director of Marketing for OnePal LLC, says the coupons give our users yet another tool to realize savings using the onePAL.com website.
OnePal gives its users a powerful, user-friendly format that harnesses the power of the Web to help them make the best shopping decisions. OnePAL.coms homepage shows dynamically updated lists of featured products based on popularity and products most recently searched. The site has pictures of featured products.
Both features are...
OnePAL Adds Searchable Coupons, Holiday Gift Idea Center
Plasma tv > OnePAL Adds Searchable Coupons, Holiday Gift Idea Center
HDTV: Buying Guide, Part One
There's never been a better time than now to buy a high-definition television (HDTV). Whether your primary source of television programming is local over-the-air broadcasts, cable or digital satellite TV, you will find that there is now a wealth of high-definition programs available. If you have a standard-definition television you will also enjoy
all of your widescreen-format DVDs that much more on a HDTV. And with Toshiba now shipping their first-generation HD-DVD players and Blu-Ray players coming to North America next month, there are even more reasons why it makes sense to take the
plunge and buy an HDTV.
Now that you're convinced you need to go out and buy a brand new HDTV the question is what type of unit to buy. First, you should decide what size HDTV makes sense for you.
Because HDTV's have a wider aspect ratio (16:9) compared to a standard
television (4:3) you will want to choose a larger diagonal screen size for your new HDTV than...
Plasma tv > HDTV: Buying Guide, Part One
QSI Touch Screen Terminal Improves Temperature and Compressor Control for American Red Cross Blood and Plasma Storage Rooms
SALT LAKE CITY, UTAH (ContentDesk) November 2, 2005 -- QSI Corporation, manufacturer of rugged operator interface and mobile data terminals, was selected by Pro Refrigeration Inc., developers of chilling systems, to provide the graphic human machine interface (HMI) on an advanced microprocessor driven refrigeration controller. This technology was recently implemented at the newest American Red Cross facility to improve temperature and compressor control for their blood and plasma storage rooms. This new state-of-the-art facility in Pomona, California, is the largest blood bank in the United States.After only operating a year, the Red Cross realized their existing control system was not adequate for controlling the temperature of their blood and plasma storage rooms. With blood and plasma worth millions of dollars stored in each room, variance in room or product temperature is not acceptable. Strict quality standards require little or no temperature fluctuation of the blood and plasma,...
QSI Touch Screen Terminal Improves Temperature and Compressor Control for American Red Cross Blood and Plasma Storage Rooms
Plasma tv > QSI Touch Screen Terminal Improves Temperature and Compressor Control for American Red Cross Blood and Plasma Storage Rooms
What?s the Difference Between Plasma TVs and LCD TVs?
Plasma and LCD TVs are the latest trend in home entertainment. Both offer unrivalled picture quality and resolution, while doing away with the bulkiness of the older rear-projection technologies. But with all of the hype surrounding these two types of televisions, what is the difference between them? Although they look- and are virtually priced- the same, they are not.There differences are found in the way in which they display their pictures. Plasma TV technology is made up of hundreds of thousands of little pixels, each capable of displaying red, green, and blue colors. A plasma monitor often consists of two panels, which are filled with an inert gas, such as xenon or neon.
When the pixels are excited by pulses of electricity, the gas becomes liquid, thus generating light. This light in turn then illuminates the pixels, causing them to display the appropriate color to form a picture. LCD panels function in a very similar manner. A panel of thin-film-transmitters, or TFT, sends...
What?s the Difference Between Plasma TVs and LCD TVs?
Plasma tv > What?s the Difference Between Plasma TVs and LCD TVs?
The Benefits of Titanium Rings
Titanium is an elemental metal with a wide variety of uses. Since its accidental discovery in 1791, titanium has been used to make aircraft, sporting goods such as golf clubs, automobile parts, watches, and rings. While titanium rings may not be as widespread as gold or platinum rings, they have many advantages. Titanium rings are durable, lightweight, strong, 100% hypoallergenic, and affordable. Titanium is stronger than steel and keeps its shape better than most metals used to make rings. <...
UAMS Myeloma Researchers on Team Analyzing Disease's Genetic Fingerprints -- Cancer Cell Publishes Work That Could Lead to New Treatments watches The Benefits of Titanium Rings Plasma tv
Plasma tv > The Benefits of Titanium Rings
5 Sexual Myths Destructive to Your Relationship
You have permission to publish this article electronically free of charge, providing the entire byline at the end of the article is included and the content is left unchanged. If you use it, please notify me with a copy of your publication or a url to where it can be found. For print publications, please contact me to discuss and to obtain US mailing address to send a courtesy copy. mailto:cynthiap@frognet.net5 Sexual Myths Destructive to Your Relationshipby In this era where sex seems to be on...
UAMS Myeloma Researchers on Team Analyzing Disease's Genetic Fingerprints -- Cancer Cell Publishes Work That Could Lead to New Treatments 5 Sexual Myths Destructive to Your Relationship
Plasma tv > 5 Sexual Myths Destructive to Your Relationship
Turquoise: The Native Stone
Turquoise, derived from the French word for Turkish has been adored since before 4000 BC. A lot of the early European turquoise came from the Middle East in what today is known as the country of Turkey. That is where the stone's name hails from. It is said to have healing properties, therefore beneficial to human wellness by keeping the blood pure and blood pressure low.Turquoise is December's birthstone and signifies success. It was once considered a luxury and only for the truly noble, but has...
UAMS Myeloma Researchers on Team Analyzing Disease's Genetic Fingerprints -- Cancer Cell Publishes Work That Could Lead to New Treatments jewelry Plasma tv
Plasma tv > Turquoise: The Native Stone
Cracking the Code to Increased Sales
Insurance sales is not rocket science, but there is a combination of activities that when performed together can yield great results. Award-winning health insurance professional Dan Roberts has put together 6 tips for increased sales (www.byoib.com).#1) Listen to the client. Successful salespeople always have a great and positive attitude. They make a sincere effort to help their clients, not just sell them. They listen to their clients' needs...
UAMS Myeloma Researchers on Team Analyzing Disease's Genetic Fingerprints -- Cancer Cell Publishes Work That Could Lead to New Treatments gold ring Plasma tv
Plasma tv > Cracking the Code to Increased Sales
Why is Hoodia such a sought after weight loss supplement?
Hoodia Gordonii is an unambitious little South African desert cactus type plant that has a big future ahead of it. A gift from the native San people who live in the Kalahari Desert in South Africa, this tiny plant the natives' call "Xhoba" has already began impacting the world of weight loss with its extraordinary hunger stopping traits. What the Aboriginal San Bushmen have known for a long time and the rest of us are merely beginning to realize is that Hoodia has appetite suppressant qualities...
UAMS Myeloma Researchers on Team Analyzing Disease's Genetic Fingerprints -- Cancer Cell Publishes Work That Could Lead to New Treatments hoodia Plasma tv
Plasma tv > Why is Hoodia such a sought after weight loss supplement?
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